教授
万建民
发布人: 发布日期: 2024-03-08 浏览次数:
万建民，中国工程院院士，教授，博士生导师。
办公地址：理科楼A516
办公电话：025-84396516
Email：wanjm@njau.edu.cn
研究领域：水稻遗传育种、水稻分子遗传学、水稻分子育种等。
中国工程院院士，水稻分子遗传与育种专家。长期从事水稻优异基因挖掘和分子育种研究，在国内较早提出和初步实践了作物分子设计育种。先后主持国家863、国家自然科学基金等多项重大课题。在水稻籼粳交杂种优势利用基础研究、品质优异基因挖掘、抗病虫新基因挖掘和优质高产多抗粳稻新品种选育等方面取得重要进展。克隆水稻重要新基因78个，培育新品种38个，获新品种权36项、发明专利71项。在Cell、Science、Nature、Nature Biotechnology等SCI刊物发表论文310余篇，出版专著3部。作为第一完成人，研究成果获国家科技进步一等奖和国家技术发明二等奖各1项，入选教育部2010年度高校十大科技进展、2014年度高校十大科技进展和2014年度中国科学十大进展。2012年获得何梁何利基金科学与技术进步奖。2021年获中国植物生理与植物分子生物学学会杰出成就奖。2022年获袁隆平农业科技奖。2022年获得“九三楷模”荣誉称号。入选2022年“高被引科学家”名单和全球前2%顶尖科学家榜单。
代表性论文
1. Chaolong Wang#, Jian Wang#, Jiayu Lu#, Yehui Xiong#, Zhigang Zhao,Xiaowen Yu, Xiaoming Zheng, Jing Li, Qibing Lin, Yulong Ren, Yang Hu, Xiaodong He, Chao Li, Yonglun Zeng, Rong Miao, Mali Guo, Bosen Zhang, Ying Zhu, Yunhui Zhang, Weijie Tang, Yunlong Wang, Benyuan Hao, Qiming Wang, Siqi Cheng, Xiaojuan He,Bowen Yao, Junwen Gao, Xufei Zhu, Hao Yu, Yong Wang, Yan Sun, Chunlei Zhou, Hui Dong, Xiaoding Ma, Xiuping Guo, Xi Liu, Yunlu Tian, Shijia Liu, Chunming Wang, Zhijun Cheng, Ling Jiang, Jiawu Zhou, Huishan Guo, Liwen Jiang, Dayun Tao, Jijie Chai, Wei Zhang, Haiyang Wang,* Chuanyin Wu,* Jianmin Wan,*A natural gene drive system confers reproductive isolation in rice, Cell 2023, 186: 3577–359,
2. Xiaowen Yu#, Zhigang Zhao#, Xiaoming Zheng, Jiawu Zhou, Weiyi Kong, Peiran Wang, Wenting Bai, Hai Zheng, Huan Zhang, Jing Li, Jiafan Liu, Qiming Wang, Long Zhang, Kai Liu, Yang Yu, Xiuping Guo, Jiulin Wang, Qibing Lin, Fuqing Wu, Yulong Ren, Shanshan Zhu, Xin Zhang, Zhijun Cheng, Cailin Lei, Shijia Liu, Xi Liu, Yunlu Tian, Ling Jiang, Song Ge, Chuanyin Wu†, Dayun Tao†, Haiyang Wang†, Jianmin Wan*. A selfish genetic element confers non-Mendelian inheritance in rice. Science, 2018: 360(6393): 1130-1132
3. Zhou F, Lin QB, Zhu LH, Ren YL, Zhou KN, Shabek N, Wu FQ, Mao HB, Dong W, Gan L, Ma WW, Gao H, Chen J, Yang C, Wang D, Tan JJ, Zhang X, Guo XP, Wang JL, Jiang L, Liu X, Chen WQ, Chu JF, Yan CY, Ueno K, Ito S, Asami T, Cheng ZJ, Wang J, Lei CL, Zhai HQ, Wu CY, Wang HY, Zheng N, Wan JM*. D14-SCFD3-dependent degradation of D53 regulates strigolactone signalling. Nature 2013, 504(7480): 406-410
4. Yuqiang Liu#, Han Wu#, Hong Chen, Yanling Liu, Jun He, Haiyan Kang, Zhiguang Sun, Gen Pan, Qi Wang, Jinlong Hu, Feng Zhou, Kunneng Zhou, Xiaoming Zheng, Yulong Ren, Liangming Chen, Yihua Wang, Zhigang Zhao, Qibing Lin, Fuqing Wu, Xin Zhang, Xiuping Guo, Xianian Cheng, Ling Jiang, Chuanyin Wu, Haiyang Wang, Jianmin Wan*. A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice. Nature Biotechnology. 2015, 33: 301-307
5. Shimin You#, Zhigang Zhao#, Xiaowen Yu#, Shanshan Zhu, Jian Wang, Jiawu Zhou, Dekun Lei, Weiyi Kong, Haiyuan Chen, Wenting Bai, Yanjia Xiao, Weiwei Chen, Qiming Wang, Jiayu Lu, Keyi Chen, Chunlei Zhou, Siqi Chen, Xiaoming Zheng, Dayun Tao*, Chuanyin Wu*, Jianmin Wan* A toxin-antidote system contributes to interspecific reproductive isolation in rice. Nature Communications, 2023, 14: 7528
6. Jun Yu#, Chengsong Zhu#, Wei Xuan#, Hongzhou An# Yunlu Tian, Baoxiang Wang, Wenchao Chi, Gaoming Chen, Yuwei Ge, Jin Li, Zhaoyang Dai, Yan Liu, Zhiguang Sun, Dayong Xu, ChunmingWang*, Jianmin Wan*. Genome-wide association studies identify OsWRKY53 as a key regulator of salt tolerance in rice. Nature Communications, 2023, 14: 3550
7. Weijie Tang#, Jian Ye#, Xiangmei Yao#, Pingzhi Zhao, Wei Xuan, Yunlu Tian, Yuanyan Zhang, Shuang Xu, Hongzhou An, Gaoming Chen, Jun Yu, Wei Wu, Yuwei Ge, Xiaolan Liu, Jin Li, Hanzhi Zhang, Yaqin Zhao, Bing Yang, Xingzhou Jiang, Chao Peng, Cong Zhou, William Terzaghi, Chunming Wang*, Jianmin Wan* Genome-wide associated study identifies NAC42-activated nitrate transporter conferring high nitrogen use efficiency in rice. NATURE COMMUNICATIONS. 2019, 10: 5279
8. Qibing Lin, Fuqing Wu, Peike Sheng, Zhe Zhang, Xin Zhang, Xiuping Guo, Jiulin Wang, Zhijun Cheng, Jie Wang, Haiyang Wang, Jianmin Wan*. The SnRK2-APC/CTE regulatory module mediates the antagonistic action of gibberellic acid and abscisic pathways. NATURE COMMUNICATIONS | 2015, 6:7981
9. Qi Wang, Yuqiang Liu, Jun He, Xiaoming Zheng, Jinlong Hu, Yanling Liu, Huimin Dai, Yingxin Zhang,Baoxiang Wang, Weixun Wu, He Gao, Yunhui Zhang, Xiaorong Tao, Huafeng Deng, Dingyang Yuan, Ling Jiang, Xin Zhang, Xiuping Guo, Xianian Cheng, Chuanyin Wu, Haiyang Wang, Longping Yuan, Jianmin Wan*. STV11 encodes a sulphotransferase and confers durable resistance to rice stripe virus. NATURE COMMUNICATIONS, 2014, 5:4768, DOI: 10.1038/ ncomms5768
10. Lin Q, Wang D, Dong H, Gu S, Cheng Z, Gong J, Qin R, Jiang L, Li G, Wang JL, Wu F, Guo X, Zhang X, Lei C, Wang H, Wan J*. Rice APC/C-TE controls tillering by mediating the degradation of MONOCULM 1. NATURE COMMUNICATIONS 2012, 3, 20 DOI: 10.1038/ncomms1716
11. Zhigang Zhao#, Yunhui Zhang#, Xi Liu, Xin Zhang, Shichang Liu, Xiaowen Yu, Yulong Ren, Xiaomin Zheng, Kunneng Zhou, Ling Jiang, Xiuping Guo, Ying Gai, Chuanyin Wu, Huqu Zhai, Haiyang Wang, Jianmin Wan*. A role for a dioxygenase in auxin metabolism and reproductive development in rice. Developmental Cell 2013, 27(1):113-122
12. Zhigang Zhao#, Chaolong Wang#, Xiaowen Yu#, Yunlu Tian, Wenxin Wang, Yunhui Zhang, Wenting Bai, Ning Yang, Tao Zhang,Hai Zheng, Qiming Wang, Jiayu Lu, Dekun Lei, Xiaodong He, Keyi Chen, Junwen Gao, Xi Liu, Shijia Liu, Ling Jiang,Haiyang Wang, Jianmin Wan*, Auxin regulates source-sink carbohydrate partitioning andreproductive organ development in rice. PNAS, 2022, 119(36): e2121671119. DOI: 10.1073/pnas.2121671119
13. Jun He#, Yuqiang Liu#, Dingyang Yuan, Meijuan Duan, Yanling Liu, Zijie Shen, Chunyan Yang, Zeyu Qiu, Daoming Liu, Peizheng Wen, Jie Huang, Dejia Fan, Shizhuo Xiao, Yeyun Xin, Xianian Chen, Ling Jiang, Haiyang Wang, Longping Yuan, Jianmin Wan*. An R2R3 MYB transcription factor confers brown planthopper resistance by regulating the phenylalanine ammonia-lyase pathway in rice. PNAS, 2020,117(1): 271-277
14. He Gao, Mingna Jin, Xiao-Ming Zheng, Jun Chen, Dingyang Yuan, Yeyun Xin, Maoqing Wang, Dongyi Huang, Zhe Zhang, Kunneng Zhou, Peike Sheng, Jin Ma, Weiwei Ma, Huafeng Deng, Ling Jiang, Shijia Liu, Haiyang Wang, Chuanyin Wu, Longping Yuan, Jianmin Wan*. Days to heading 7, a major quantitative locus determining photoperiod sensitivity and regional adaptation in rice. PNAS,2014, 111(46):16337-16342
15. Weixun Wu, Xiao-Ming Zheng, Guangwen Lu, Zhengzheng Zhong. He Gao, Liping Chen, Chuanyin Wu, Hong-Jun Wang, Qi Wang, Kunneng Zhou, Jiu-Lin Wang, Fuqing Wu, Xin Zhang, Xiuping Guo, Zhijun Cheng, Cailin Lei, Qibing Lin, Ling Jiang, Haiyang Wang, Song Ge, Jian-Min Wan*. The association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia. PNAS, 2013, 110 (8): 2775-2780
16. Chunlei Zhou#, Qibing Lin#, Yulong Ren#, Jie Lan, Rong Miao, Miao Feng, Xin Wang, Xi Liu, Shengzhong Zhang, Tian Pan, Jiachang Wang, Sheng Luo, Jinsheng Qian, Wenfan Luo, Changling Mou, Thanhliem Nguyen, Zhijun Cheng, Xin Zhang, Cailin Lei, Shanshan Zhu, Xiuping Guo, Jie Wang, Zhichao Zhao, Shijia Liu, Ling Jiang*, Jianmin Wan*, A CYP78As-SMG4-COPⅡ pathway promotes grain size in rice. The Plant Cell,2023, 35: 4325–4346
17. Erchao Duan#, Qibing Lin#, Yihua Wang#, Yulong Ren, Huan Xu, Yuanyan Zhang, Yunlong Wang, Xuan Teng, Hui Dong, Yupeng Wang, Xiaokang Jiang, Xiaoli Chen, Jie Lei, Hang Yang, Rongbo Chen, Ling Jiang, Haiyang Wang, Jianmin Wan,* The transcriptional hub SHORT INTERNODES1 integrates hormone signals to orchestrate rice growth and development. The Plant Cell. 2023: 35: 2871–2886
18. Tianzhen Liu, Xin Zhang, Huan Zhang, Zhijun Cheng, Jun Liu, Chunlei Zhou, Sheng Luo, Weifeng Luo, Shuai Li, Xinxin Xing, Yanqi Chang, Cuilan Shi, Yulong Ren, Shanshan Zhu, Cailin Lei, Xiuping Guo, Jie Wang, Zhichao Zhao, Haiyang Wang, Huqu Zhai, Qibing Lin, Jianmin Wan*, Dwarf and High Tillering1 represses rice tillering through mediating the splicing of D14 pre-mRNA, The Plant Cell, 2022, 34: 3301–331
19. Qibing Lin#, Zhe Zhang#, Fuqing Wu, Miao Feng, Yao Sun, Weiwei Chen, Zhijun Cheng, Xin Zhang, Yulong Ren, Cailin Lei, Shanshan Zhu, Jie Wang, Zhichao Zhao, Xiuping Guo, Haiyang Wang, Jianmin Wan*. The APC/CTE E3 Ubiquitin Ligase Complex Mediates the Antagonistic Regulation of Root Growth and Tillering by ABA and GA. The Plant Cell, 2020, 32: 1973-1987
20. Yulong Ren#, Yihua Wang#, Tian Pan, Yunlong Wang, Yongfei Wang, Lu Gan, Zhongyan Wei, Fan Wang, Mingming Wu, Ruonan Jing, Jiachang Wang, Gexing Wan, Xiuhao Bao, Binglei Zhang, Pengcheng Zhang, Yu Zhang, Yi Ji, Cailin Lei, Xin Zhang, Zhijun Cheng, Qibing Lin, Shanshan Zhu, Zhichao Zhao, Jie Wang, Chuanyin Wu, Lijuan Qiu, Haiyang Wang, Jianmin Wan*. GPA5 Encodes a Rab5a Effector Required for Post-Golgi Trafficking of Rice Storage Proteins, The Plant Cell. 2020, 32: 758–777.
21. Jiachang Wang#, Xi Liu#, An Zhang, Yulong Ren, Fuqing Wu, Gang Wang, Yang Xu, Cailin Lei, Shanshan Zhu, Tian Pan, Yongfei Wang, Huan Zhang, Fan Wang, Yan-Qiu Tan, Yupeng Wang, Xin Jin, Sheng Luo, Chunlei Zhou, Xiao Zhang, Jinling Liu, Shuai Wang, Lingzhi Meng, Yihua Wang, Xi Chen, Qibing Lin, Xin Zhang, Xiuping Guo, Zhijun Cheng, Jiulin Wang, Yunlu Tian, Shijia Liu, Ling Jiang, Chuanyin Wu, Ertao Wang, Jian-Min Zhou, Yong-Fei Wang, Haiyang Wang, Jianmin Wan*. A cyclic nucleotide-gated channel mediates cytoplasmic calcium elevation and disease resistance in rice. Cell Research 2019, 29: 820-831
22. Weng JF, Gu SH, Wan XY, Gao H, Guo T, Su N, Lei CL, Zhang X, Cheng ZJ, Guo XP, Wang JL, Jiang L, Zhai HQ, Wan JM*. Isolation and initial characterization of GW5, a major QTL associated with rice grain width and weight. Cell Research (2008) 18: 1199-1209.
23. Wang YH, Liu SJ, Ji SL, Zhang WW, Wang CM, Jiang L, Wan JM* Fine mapping and marker-assisted selection of a low glutelin content gene Lgc-2(t) in rice. Cell Research, 2005, 15(8): 622-630
24. Jiafan Liu#, Jun Chen#, Xiaoming Zheng, Fuqing Wu, Qibing Lin, Yueqin Heng, Peng Tian, ZhiJun Cheng, Xiaowen Yu, Kunneng Zhou, Xin Zhang, Xiuping Guo, Jiulin Wang, Haiyang Wang*, Jianmin Wan*. GW5 acts in the brassinosteroid signaling pathway to regulate grain width and weight in rice. NATURE PLANTS, 2017, 3, 17043
25. Cai M, Zhu S, Wu M, Zheng X, Wang J, Zhou L, Zheng T, Cui S, Zhou S, Li C, Zhang H, Chai J, Zhang X, Jin X, Cheng Z, Zhang X, Lei C, Ren Y, Lin Q, Guo X, Zhao L, Wang J, Zhao Z, Jiang L, Wang H, Wan J*. DHD4, a CONSTANS-like family transcription factor, delays heading date by affecting the formation of the FAC complex in rice. Mol. Plant. 2021,14, 330–343.
26. Wang J, Ren Y, Liu X, Luo S, Zhang X, Liu X, Lin Q, Zhu S, Wan H, Yang Y, Zhang Y, Lei B, Zhou C, Pan T, Wang Y, Wu M, Jing R, Xu Y, Han M, Wu F, Lei C, Guo X, Cheng Z, Zheng X, Wang Y, Zhao Z, Jiang L, Zhang X, Wang YF, Wang H, Wan J*. Transcriptional activation and phosphorylation of OsCNGC9 confer enhanced chilling tolerance in rice. Mol. Plant. 2021,14, 315–329
27. Zhou Shirong, Cai Liang, Wu Haoqin, Wang Baoxiang, Gu Biao, Cui Song, Huang Xiaolong, Xu Zhuang, Hao Benyuan, Hou Haigang, Hu Yuan, Li Chao, Tian Yunlu, Liu Xi, Chen Liangming, Liu Shijia, Jiang Ling, Wan Jianmin*. Fine tuning rice heading date through multiplex editing of the regulatory regions of key genes by CRISPR-Cas9, Plant Biotechnology Journal, 2024, 22:751-758
28. Zhang Ao#, Shan Tiaofeng#, Sun Yan#, Chen Zhipeng, Hu Jianjian, Hu Zhichao, Ming Ziheng, Zhu Zhitao, Li Xue, He Jun, Liu Shijia, Jiang Ling, Dong Xiaoou, Wu Yufeng, Wang Yanpeng, Liu Yuqiang, Li Chao*, Wan Jianmin*. Directed evolution rice genes with randomly multiplexed sgRNAs assembly of base editors. Plant Biotechnology Journal, 2023, 21: 2597–2610
29. Dekun Lei#, Anqi Jian#, Xianbo Huang#, Xi Liu, Liangming Chen, Wenting Bai, Siqi Cheng, Xiaodong He,Yehui Xiong, Xiaowen Yu, Chaolong Wang, Hai Zheng, Shimin You, Qiming Wang, Jiayu Lu, Yang Hu, Zhenwei Xie, Ling Jiang, Xin Zhang, Yulong Ren, Cailin Lei, Zhijun Cheng, Qibing Lin, Chuanyin Wu, Shanshan Zhu*, Zhigang Zhao,* Jianmin Wan,*Anther-specific expression of OsRIP1 causes dominant male sterility in rice. Plant Biotechnology Journal, 2023, 21: 1932–1934.
30. Gaoming Chen#, Wei Xuan#, Pingzhi Zhao#, Xiangmei Yao, Chao Peng, Yunlu Tian, Jian Ye, Baoxiang Wang, Jun He, Wenchao Chi, Jun Yu, Yuwei Ge, Jin Li, Zhaoyang Dai, Dayong Xu, Chunming Wang*, Jianmin Wan*. OsTUB1 confers salt insensitivity by interacting with Kinesin13A to stabilize microtubules and ion transporters in rice. New Phytologist 2022, 235: 1836–1852