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王益华

姓名:王益华

性别:男

毕业院校:南京农业大学

最高学位:博士

办公地址:理科楼A508

办公电话:025-84396628

电子邮箱:yihuawang@njau.edu.cn

现为教授,博士生导师,中国作物学会理事,中国作物学会分子育种分会委员和水稻育种分会委员。2002年毕业于南京农业大学农学院,2007年博士毕业获理学(遗传学)博士学位。2007年至2010年在南京农业大学作物学流动站进行了三年的博士后研究工作,2010年9月正式留校任教。主要从事稻米品质形成的分子机制研究,克隆并鉴定了一系列参与水稻谷蛋白分选和淀粉合成调控途径的关键基因,初步构建了水稻谷蛋白分选分子网络途径,并参与培育肾脏病人专用功能性水稻新品系。以第一作者(含共一)和共同通讯作者在Plant Cell、PLoS Genetics、Plant Physiology、Plant Journal、New Phytologist、Molecular Plant、Journal of Experimental Botany、Cell Research等杂志发表SCI文章三十多篇,其中影响因子>5的文章有18篇,获得授权专利十多项。先后主持中国博士后特别基金、国家自然科学基金集成项目、国家自然科学基金面上项目、科技部转基因专项、科技支撑计划、国家重点研发计划、江苏省农业科技自主创新项目等课题二十多项,2010年入选"教育部新世纪人才支持计划",2012年入选南京农业大学首批“钟山学术新秀”,同年获农学院英才奖励基金“优秀新人奖”,2017年获得“大北农青年学者奖”,2018年获“江苏省杰出青年基金”资助。

 近年来发表代表性文章:

1Yulong Ren#, Yihua Wang#, Tian Pan#, Yunlong Wang#, Yongfei Wang, Lu Gan, Zhongyan Wei, Fan Wang, Mingming Wu, Ruonan Jing, Jiachang Wang, Gexing Wan, Xiuhao Bao, Binglei Zhang, Pengcheng Zhang, Yu Zhang, Yi Ji, Cailin Lei, Xin Zhang, Zhijun Cheng, Qibing Lin, Shanshan Zhu, Zhichao Zhao, Jie Wang, Chuanyin Wu, Lijuan Qiu, Haiyang Wang, and Jianmin Wan*.  GPA5 encodes a Rab5a effector required for post-Golgi trafficking of rice storage proteins. Plant Cell, 2020, DOI: https://doi.org/10.1105/tpc.19.00863

2Jianping Zhu#, Yulong Ren#, Yunlong Wang, Feng Liu, Xuan Teng, Yuanyan Zhang, Erchao Duan, Mingming Wu, Mingsheng Zhong, Yuanyuan Hao, Xiaopin Zhu, Jie Lei, Yongfei Wang, Yanfang Yu, Tian Pan, Yiqun Bao, Yihua Wang* and Jianmin Wan*. OsNHX5-mediated pH homeostasis is required for post-Golgi trafficking of seed storage proteins in rice endosperm cells. BMC Plant Biology, 2019, 19, 295

3Yinglun Sun#, Yunlu Tian#, Shuhan Cheng, Yunlong Wang, Yuanyuan Hao, Jianping Zhu, Xiaopin Zhu, Yuanyan Zhang, Mingzhou Yu, Jie Lei, Xiuhao Bao, Hongming Wu, Yihua Wang* and Jianmin Wan*. WSL6 encoding an Era-type GTP-binding protein is essential for chloroplast development in rice. Plant Molecular Biology, 2019, 100(6): 635-645

4Erchao Duan#, Yihua Wang#, Xiaohui Li, Qibing Lin, Ting Zhang, Huan Zhang, Ling Jiang, Jiulin Wang, Cailin Lei, Xin Zhang, Xiuping Guo, Haiyang Wang, and Jianmin Wan*.  OsSHI1 regulates plant architecture through modulating the transcriptional activity of IPA1 in rice. Plant Cell, 2019, 31(5), 1026-1042.

5Yuanyuan Hao#, Yunlong Wang#, Mingming Wu, Xiaopin Zhu, Xuan Teng, Yinglun Sun, Jianping Zhu, Yuanyan Zhang, Ruonan Jing, Jie Lei, Jingfang Li, Xiuhao Bao, Chunming Wang, Yihua Wang*, and Jianmin Wan*. A nucleus-localized PPR protein OsNPPR1 is important for mitochondrial function and endosperm development in rice. Journal of Experimental Botany, 2019, 70(18): 4705-4720

6Mingming Wu#, Yulong Ren#, Maohong Cai, Yunlong Wang, Shanshan Zhu, Jianping Zhu, Yuanyuan Hao, Xuan Teng, Xiaopin Zhu, Ruonan Jing, Huan Zhang, Mingsheng Zhong, Yongfei Wang, Cailin Lei, Xin Zhang, Xiuping Guo, Zhijun Cheng, Qibing Lin, Jie Wang, Ling Jiang, Yiqun Bao, Yihua Wang*, and Jianmin Wan*. Rice FLOURY ENDOSPERM10 encodes a pentatricopeptide repeat protein that is essential for the trans-splicing of mitochondrial nad1 intron 1 and endosperm development. New Phytologist, 2019, 223, 736-750.

7Xuan Teng, Mingsheng Zhong, Xiaopin Zhu, Chunming Wang, Yulong Ren, Yunlong Wang, Huan Zhang, Ling Jiang, Di Wang, Yuanyuan Hao, Mingming Wu, Jianping Zhu, Xin Zhang, Xiuping Guo, Yihua Wang* and Jianmin Wan*. FLOURY ENDOSPERM16 encoding a NAD-dependent cytosolic malate dehydrogenase plays an important role in starch synthesis and seed development in rice. Plant Biotechnology Journal, 2019, 17(10), 1914-1927

8Mingsheng Zhong#, Xi Liu#, Feng Liu,Yulong Ren, Yunlong Wang, Jianping Zhu, Xuan Teng, Erchao Duan, Fan Wang, Huan Zhang, Mingming Wu, Yuanyuan Hao, Xiaopin Zhu,Ruonan Jing, Xiuping Guo, Ling Jiang, Yihua Wang*, and Jianmin Wan*. FLOURY ENDOSPERM12 encoding Alanine aminotransferase 1 regulates carbon and nitrogen metabolism in rice. Journal of Plant Biology, 2019, 62, 61-73.

9Tingting Hu#, Yunlu Tian#, Jianping Zhu, Yunlong Wang, Ruonan Jing, Jie Lei, Yinglun Sun, Yanfang Yu, Jingfang Li, Xiaoli Chen, Xiaopin Zhu, Yuanyuan Hao, Linglong Liu, Yihua Wang*, and Jianmin Wan*. OsNDUFA9 encoding a mitochondrial complex I subunit is essential for embryo development and starch synthesis in rice. Plant Cell Reports, 2018, 37, 1667-1679.

10Yihua Wang#, Feng Liu#, Yulong Ren#, Yunlong Wang, Xi Liu, Wuhua Long, Di Wang, Jianping Zhu, Xiaopin Zhu, Ruonan Jing, Mingming Wu, Yuanyuan Hao, Ling Jiang, Chunming Wang, Haiyang Wang, Yiqun Bao, and Jianmin Wan. GOLGI TRANSPORT 1B regulates protein export from the endoplasmic reticulum in rice endosperm cells. Plant Cell, 2016, 28, 2850-2865.

11Xiaopin Zhu#, Xuan Teng#, Yunlong Wang, Yuanyuan Hao, Ruonan Jing, Yongfei Wang, Yi Liu, Jianping Zhu, Mingming Wu, Mingsheng Zhong, Xiaoli Chen, Yuanyan Zhang, Wenwei Zhang, Chunming Wang, Yihua Wang*, and Jianmin Wan*. FLOURY ENDOSPERM11 encoding a plastid heat shock protein 70 is essential for amyloplast development in rice. Plant Science, 2018, 277, 89-99.

12 Yang Xu#, Jie Yang#, Yihua Wang#, Jiachang Wang, Yang Yu, Yu Long, Yunlong Wang, Huan Zhang, Yulong Ren, Jun Chen, Ying Wang, Xin Zhang, Xiuping Guo, Fuqing Wu, Shanshan Zhu, Qibing Lin, Ling Jiang, Chuanyin Wu, Haiyang Wang and Jianmin Wan*. OsCNGC13 promotes seed-setting rate by facilitating pollen tube growth in stylar tissues. PLoS Genetics, 2017, 13(7): e1006906. https://doi.org/10.1371/journal. pgen.1006906

13 Mei Niu#, Yihua Wang#, Chunming Wang, Jia Lyu, Yunlong Wang, Hui Dong, Wuhua Long, Di Wang, Weiyi Kong, Liwei Wang, Xiuping Guo, Liting Sun, Tingting Hu, Huqu Zhai, Haiyang Wang and Jianmin Wan*. ALR encoding dCMP deaminase is critical for DNA damage repair, cell cycle progression and plant development in rice. Journal of Experimental Botany, 2017, 68(21-22): 5773-5786.

14Di Wang#, Yunlong Wang, Wuhua Long, Mei Niu, Zhigang Zhao, Xuan Teng, Xiaopin Zhu, Jianping Zhu, Yuanyuan Hao, Yongfei Wang, Yi Liu, Ling Jiang, Yihua Wang#,* and Jianmin Wan*. SGD1, a key enzyme in tocopherols biosynthesis, is essential for plant development and cold tolerance in rice. Plant Science, 2017, 260, 90-100.

15Liting Sun#Yihua Wang#, Ling-long Liu, Chunming Wang, Ting Gan, Zhengyao Zhang, Yunlong Wang, Di Wang, Mei Niu, Wuhua Long, Xiaohui Li, Ming Zheng, Ling Jiang, and Jianmin Wan*. Isolation and characterization of a spotted leaf 32 mutant with early leaf senescence and enhanced defense response in rice. Scientific Reports, 2017, 7, 41846, doi:10.1038/srep41846.

16Yihua Wang#, Di Wang#, Ting Gan, Linglong Liu, Wuhua Long, Yunlong Wang, Mei Niu, Xiaohui Li, Ming Zheng, Ling Jiang and Jianmin Wan. CRL6, a member of the CHD protein family, is required for crown root development in rice. Plant Physiology and Biochemistry, 2016, 105, 185-194.

17Ming Zheng#Yihua Wang#, Xi Liu, Juan Sun, Yunlong Wang, Yang Xu, Jia Lv, Wuhua Long, Xiaopin Zhu, Xiuping Guo, Ling Jiang, Chunming Wang and Jianmin Wan. The RICE MINUTE-LIKE1 (RML1) gene, encoding a ribosomal large subunit protein L3B, regulates leaf morphology and plant architecture in rice. Journal of Experimental Botany, 2016, 67, 3457-3469.    

18Yunlong Wang#, Chunming Wang, Ming Zheng, Jia Lyu, Yang Xu, Xiaohui Li, Mei Niu, Wuhua Long, Di Wang, Haiyang Wang, Willianm Terzaghi, Yihua Wang#,* and Jianmin Wan*. WHITE PANICLE1, a Val-tRNA synthetase regulating chloroplast ribosome biogenesis in rice, is essential for early chloroplast development. Plant Physiology, 2016, 170, 2110-2123.

19Erchao Duan#Yihua Wang#, Linglong Liu, Jianping, Zhu, Mingsheng Zhong, Huan Zhang, Sanfeng Li, Baoxu Ding, Xin Zhang, Xiuping Guo, Ling Jiang, and Jianmin Wan*. Pyrophosphate:fructose-6-phosphate 1-phosphotransferase (PFP) regulates carbon metabolism during grain filling in rice. Plant Cell Reports, 2016, 35, 1321-1331.  

20Ming Zheng#Yihua Wang#, Yunlong Wang, Chunming Wang, Yulong Ren, Jia Lv, Cheng Peng, Tao Wu, Kai Liu, Shaolu Zhao, Xi Liu, Xiuping Guo, Ling Jiang, William Terzaghi and Jianmin Wan.  DEFORMED FLORAL ORGAN1 (DFO1) regulates floral organ identity by epigenetically repressing expression of OsMADS58  in rice (Oryza sativa). New Phytologist, 2015, 206, 1476-1490. 

21Yulong Ren#Yihua Wang#, Feng Liu#, Kunneng Zhou, Yu Ding, Feng Zhou, Ying Wang, Kai Liu, Lu Gan, Weiwei Ma, Xiaohua Han, Xin Zhang, Xiuping Guo, Fuqing Wu, Zhijun Cheng, Jiulin Wang, Cailin Lei, Qibing Lin, Ling Jiang, Chuanyin Wu, Yiqun Bao, Haiyang Wang and Jianmin Wan*. Glutelin precursor accumulation3 encodes a regulator of post-Golgi vesicular traffic essential for vacuolar protein sorting in rice endosperm. Plant Cell, 2014, 26, 410-425.    

22Cheng Peng#, Yihua Wang#, Feng Liu, Yulong Ren, Kunneng Zhou, Jia Lv, Ming Zheng, Shaolu Zhao, Long Zhang, Chunming Wang, Ling Jiang, Xin Zhang, Xiuping Guo, Yiqun Bao and Jianmin Wan*. FLOURY ENDOSPERM6 encodes a CBM48 domain-containing protein involved in regulation of compound granule formation and starch synthesis in rice endosperm. Plant Journal, 2014, 77, 917-930.    

23Yang Xu#Yihua Wang#, Qizhang Long, Jiexue Huang, Yunlong Wang, Kunneng Zhou, Ming Zheng, Juan Sun, Hong Chen, Saihua Chen, Ling Jiang, Chunming Wang and Jianmin Wan*. Overexpression of OsZHD1, a zinc finger homeodomain class homeobox transcription factor, induces abaxially curled and dropping leaf in rice. Planta, 2014, 239, 803-816.   

24Jieqin Li#,Yihua Wang#, Juntao Chai, Lihua Wang, Chunming Wang, Wuhua Long, Di Wang, Yunlong Wang, Ming Zheng, Cheng Peng, Mei Niu, Jianmin Wan*. Green-revertible chlorina 1(Grc1) is required for the biosynthesis of chlorophyll and the early development of chloroplast in rice. Journal of plant biology, 2013, 56 (5), 326-335   

25Feng Liu#, Yulong Ren#, Yihua Wang#, Cheng Peng, Kunneng Zhou, Jia Lv, Xiuping Guo, Xin Zhang, Mingsheng Zhong, Shaolu Zhao, Ling Jiang, Haiyang Wang, Yiqun Bao and Jianmin Wan. OsVPS9A functions cooperatively with OsRAB5A to regulate post-Golgi dense vesicle-mediated storage protein trafficking to protein storage vacuole in rice endosperm cells. Molecular Plant, 2013, 6(6), 1918-1932.    

26Xiaohua Han#Yihua Wang#, Xi Liu, Lin Jiang, Yulong Reng, Feng Liu, Cheng Peng, Jingjing Li, Ximing Jin, Fuqing Wu, Jiuling Wang, Xiuping Guo, Xin Zhang, Zhijun Cheng and Jianmin Wan. The failure to express a protein disulfide isomerase-like protein results in a floury endosperm and an endoplasmic reticulum stress response in rice. Journal of Experimental Botany, 2012, 63, 121-130.  

27Yihua Wang#, Yulong Ren, Xi Liu, Ling Jiang, Liangming Chen, Xiaohua Han, Mingna Jin, Shijia Liu, Feng Liu, Jia Lv, Kunneng Zhou, Ning Su, Yiqun Bao and Jianmin Wan*. OsRab5a regulates endomembrane organization and storage protein trafficking in rice endosperm cells. Plant Journal, 2010, 64, 812-824.

28Yihua Wang#, Susong Zhu, Shijia Liu, Ling Jiang, Liangming Chen, Yulong Ren, Xiaohua Han, Feng Liu, Sulan Ji, Xi Liu and Jianmin Wan*. The vacuolar processing enzyme OsVPE1 is required for efficient glutelin processing in rice. Plant Journal, 2009, 58, 606-617.

主持项目:

1、江苏省自然科学基金--杰出青年基金项目,BK20180024,水稻谷蛋白转运途径关键基因的功能解析,2018.7-2021.6, 100万元,在研,主持;

2、国家自然基金面上项目,31971908,GPA11调控水稻谷蛋白内质网输出的分子机制研究,2020-2023,58万,在研,主持;

3、国家自然科学基金集成项目子课题,91935301,水稻产量与品质协同调控的遗传机制,2020.1-2021.12, 228.5万,在研,主持;

4、国家自然基金面上项目,31671652,GPA1/OsRab5a互作蛋白RIP1调控水稻谷蛋白运输的分子机制研究,2017. 1-2020.12,62万元(直接费用),在研,主持;

5、江苏农业自主创新项目,CX19(19)1002,水稻分子设计精准育种高效技术体系研究,2019-2024,350万,在研,主持;

6、转基因专项子课题,2016ZX08009003-004,水稻、大豆和棉花品质改良关键基因克隆及功能验证,2016. 1-2018.12,253.2万元,在研,主持;

7、重点研发计划子课题,稻米外观、营养和健康功能品质形成与改良的分子基础,2016YFD0100501,2016. 7-2020.12,139万元,在研,主持;

8、重点研发计划子课题,水稻抗逆性状功能基因组研究,2016YFD0100903-7,2016.7-2020.12,140万元,在研,主持;

9、南京农业大学中央高校基本科研业务费重大专项,KYTZ201601,稻米品质形成相关基因的克隆和功能研究,2016.1-2019.12,300万元,在研,主持;

10、国家自然基金面上项目,31371598,水稻发育胚乳中控制谷蛋白ER-Golgi运输关键基因OsGot1的功能研究,2014. 1-2017.12,80万元,结题,主持;

11、教育部新世纪人才支持计划,NCET-10-0497,2011.1-2013.12, 50万元;结题,主持;

12、国家自然基金面上项目,30971757,水稻谷蛋白合成途径关键基因OsRab5a的功能研究,2010.1-2012.12,31万元,结题,主持;

13、国家科技支撑计划,2011BAD35B02-02,长江流域粳稻新品种培育与扩繁、2011.1-2015.12,286万元,结题,主持。

14、国家科技部转基因专项,2011ZX08009-003-004、水稻谷蛋白分选关键基因的克隆与功能鉴定,2011.1-2012.12,36万元,结题,主持。

15、中央高校基本科研业务费,KYZ201101,OsRab5a和OsVPS9a调控水稻谷蛋白分选的分子机制,2011.5-2014.4,40万元,结题,主持。

16、江苏省博士后基金,0702030B,水稻谷蛋白合成途径关键基因的图位克隆与功能研究,2007.7-2009.6,3万元,结题,主持;

17、中国博士后基金,20070421025,水稻谷蛋白突变体Q4041突变基因的克隆与功能鉴定,2007.7-2009.6,3万元,结题,主持;

18、中国博士后特别基金,200801378,水稻谷蛋白合成途径关键基因OsRab5a的功能研究,2009.1-2010.12,10万元,结题,主持;